Inomero ya Cataloge | RC-CF29 |
Incamake | Kumenya antine ya Canine Dirofilaria immitis, antibodiyite za Anaplasma, antibodiyite E. canis muminota 10 |
Ihame | Intambwe imwe yubudahangarwa bw'umubiri |
Intego zo Kumenya | CHW Ag: Dirofilaria immitis antigens Anapalsma Ab: Antibodies za AnaplasmaE. canis Ab: E. antibodiyite |
Icyitegererezo | Canine Amaraso Yuzuye, Plasma cyangwa Serumu |
Igihe cyo gusoma | Iminota 10 |
Umubare | Agasanduku 1 (kit) = ibikoresho 10 (Gupakira kugiti cyawe) |
Ibirimo | Ikizamini cyibizamini, icupa rya Buffer, hamwe nigitonyanga |
Ububiko | Ubushyuhe bwo mucyumba (kuri 2 ~ 30 ℃) |
Igihe kirangiye | Amezi 24 nyuma yo gukora |
Icyitonderwa | Koresha muminota 10 nyuma yo gufunguraKoresha urugero rwicyitegererezo (0,01 ml yigitonyanga) Koresha nyuma yiminota 15 ~ 30 kuri RT niba bibitswe mubihe bikonje Reba ibisubizo by'ibizamini bitemewe nyuma yiminota 10 |
Indwara z'umutima zikuze zikura santimetero nyinshi z'uburebure kandi ziba mu mitsi iva mu bihaha aho ishobora kubona intungamubiri zihagije.Indwara z'umutima ziri mu mitsi zitera gucana no gukora hematoma.Umutima rero, ugomba kuvoma kenshi kuruta mbere nkuko inzoka zumutima ziyongera mumibare, bikabuza imiyoboro.
Iyo kwandura kwangiritse (inzoka zirenga 25 zibaho mu mbwa 18 kg), inzoka zumutima zinjira muri atrium iburyo, bikabuza gutembera kwamaraso.
Iyo umubare winzoka zumutima ugeze kurenga 50, barashobora gufata
atrium na ventricles.
Iyo yanduye indwara zumutima zirenga 100 mugice cyiburyo cyumutima, imbwa itakaza imikorere yumutima amaherezo igapfa.Ibi byica
phenomenon yitwa "Syndrom ya Caval."
Bitandukanye nizindi parasite, inzoka zumutima zitera udukoko duto bita microfilariya.Microfilariya mu mibu yimukira mu mbwa iyo umubu unywa amaraso n'imbwa.Indwara z'umutima zishobora kubaho mubakira imyaka 2 zipfa iyo zitimukiye mubandi bakiriye muri kiriya gihe.Parasite iba mu mbwa itwite irashobora kwanduza urusoro rwayo.
Gusuzuma hakiri kare inzoka z'umutima ni ngombwa cyane mu kuzikuraho.Indwara z'umutima zinyura mu ntambwe nyinshi nka L1, L2, L3 harimo icyiciro cyo kwanduza imibu kugirango kibe inzoka z'umutima zikuze.
Microfilariya mu mibu ikura muri L2 na L3 parasite zishobora kwanduza imbwa mu byumweru byinshi.Gukura biterwa nikirere.Ubushyuhe bwiza kuri parasite burenga 13.9 ℃.
Iyo umubu wanduye urumye imbwa, microfilariya ya L3 yinjira mu ruhu rwayo.Mu ruhu, microfilariya ikura muri L4 ibyumweru 1 ~ 2.Nyuma yo kuba mu ruhu amezi 3, L4 ikura muri L5, ijya mumaraso.
L5 nkuburyo bwinzoka zumutima zikuze zinjira mumutima no mumitsi yimitsi aho amezi 5 ~ 7 nyuma yumutima utera udukoko.
Indwara yinzoka yumutima irakira neza mubihe byinshi.Kurandura inzoka zose z'umutima, gukoresha imiti ninzira nziza.Kumenya hakiri kare inzoka z'umutima bizamura igipimo cyo kuvura.Ariko, mugihe cyanyuma cyo kwandura, ingorane zirashobora kubaho, bigatuma kuvura bigorana.
Bagiteri Anaplasma phagocytophilum (yahoze yitwa Ehrilichia phagocytophila) irashobora gutera kwandura amoko menshi y’inyamaswa harimo n’abantu.Indwara iri mu matungo yo mu rugo nayo yitwa tick-borne fever (TBF), ikaba imaze nibura imyaka 200.Indwara ya bagiteri yumuryango Anaplasmataceae ni garama-mbi, idafite moteri, coccoide yibinyabuzima bya ellipsoide, bitandukanye mubunini kuva kuri 0.2 kugeza kuri 2.0um.Nibitegekwa na aerobes, kubura inzira ya glycolitike, kandi byose ni parasite idasanzwe.Amoko yose yo mu bwoko bwa Anaplasma atuye muri vacuole itondekanye muri selile zidakuze cyangwa zikuze za hematopoietic ya selile y’inyamabere.Phagocytophilum yanduza neutrophile kandi ijambo granulocytotropic ryerekeza kuri neutrophile yanduye.Ni gake ibinyabuzima, byabonetse muri eosinofile.
Anaplasma phagocytophilum
Ibimenyetso bisanzwe bivura kanseri ya anaplasmose harimo umuriro mwinshi, ubunebwe, kwiheba na polyarthritis.Ibimenyetso bya neurologic (ataxia, gufatwa no kubabara ijosi) nabyo birashobora kugaragara.Indwara ya Anaplasma phagocytophilum ntishobora guhitana abantu keretse iyo igoye nizindi ndwara.Igihombo kiziguye, ubumuga bwo gutakaza no gutakaza umusaruro byagaragaye muntama.Gukuramo inda no kwangirika kwa spermatogenezi mu ntama n'inka byanditswe.Uburemere bwubwandu buterwa nimpamvu nyinshi, nkimpinduka za Anaplasma phagocytophilum zirimo, izindi ndwara ziterwa na virusi, imyaka, imiterere yumubiri ndetse nubuzima bwa nyirubwite, nibintu nkikirere nubuyobozi.Twabibutsa ko ivuriro ryigaragaza mu bantu ritangirira ku ndwara yoroheje yibicurane nk'ibicurane, kugeza n'indwara yangiza ubuzima.Nyamara, indwara nyinshi zabantu zishobora kuvamo bike cyangwa ntabigaragaza.
Anaplasma phagocytophilum yanduzwa na tike ya ixodide.Muri Reta zunzubumwe zamerika ibice nyamukuru ni Ixode scapularis na Ixode pacificus, mugihe Ixode ricinus yasanze aribwo buryo nyamukuru bwa exophilique i Burayi.Anaplasma phagocytophilum yanduzwa naya matiku ya vector, kandi nta kimenyetso cyerekana kwandura transovarial.Ubushakashatsi bwinshi kugeza ubu bwakoze ubushakashatsi ku kamaro k’inyamabere z’inyamabere za A. phagocytophilum hamwe n’ingirabuzimafatizo zayo byibanze ku nzoka ariko iki kinyabuzima gifite inyamaswa nini z’inyamabere, zanduza injangwe zororerwa mu rugo, imbwa, intama, inka, n'amafarasi.
Indirect immunofluorescence isuzuma nikizamini nyamukuru gikoreshwa mugutahura ubwandu.Icyiciro cya serumu ikaze kandi ihindagurika irashobora gusuzumwa kugirango harebwe impinduka enye muri titer ya antibody kuri Anaplasma phagocytophilum.Imitsi idasanzwe (morulea) igaragara muri granulocytes kuri Wright cyangwa Gimsa isize amaraso.Uburyo bwa polymerase reaction (PCR) bukoreshwa mugutahura ADN ya Anaplasma phagocytophilum.
Nta rukingo ruboneka kugirango wirinde kwandura Anaplasma phagocytophilum.Kwirinda bishingiye ku kwirinda kwirinda kwandura amatiku (Ixode scapularis, Ixode pacificus, na Ixode ricinus) kuva mu mpeshyi kugeza kugwa, gukoresha imiti igabanya ubukana bwa antacariside, no gukoresha poropagitike ya doxycycline cyangwa tetracycline igihe usuye Ixode scapularis, Ixode pacificus, na Ixode ricxin uturere twanduye.
Ehrlichia canis ni parasite ntoya ninkoni yanduzwa nimbwa yimbwa yumukara, Rhipicephalus sanguineus.E. canis nintandaro ya ehrlichiose ya kera mu mbwa.Imbwa zirashobora kwandura spp nyinshi za Ehrlichia.ariko ikunze gutera kanseri ehrlichiose ni E. canis.
E. canis ubu bizwi ko yakwirakwiriye muri Amerika, Uburayi, Amerika y'Epfo, Aziya na Mediterane.
Imbwa zanduye zitavuwe zirashobora guhinduka abatwara indwara imyaka myinshi hanyuma amaherezo igapfa kubera kuva amaraso menshi.
Indwara ya Ehrlichia canis mu mbwa igabanijwemo ibyiciro 3;
ICYICIRO CYA ACUTE: Mubisanzwe nicyiciro cyoroheje cyane.Imbwa izaba idafite urutonde, ibiryo, kandi irashobora kuba yaguye lymph node.Hashobora no kugira umuriro ariko gake ni gake iki cyiciro cyica imbwa.Benshi basiba ibinyabuzima bonyine ariko bamwe bazakomeza mugice gikurikira.
ICYICIRO CYA SUBCLINICAL: Muri iki cyiciro, imbwa igaragara nkibisanzwe.Ibinyabuzima byacengeye mu ruhago kandi byihishe hanze.
ICYICIRO CYA CHRONIC: Muri iki cyiciro imbwa irongera irarwara.Imbwa zigera kuri 60% zanduye E. canis zizagira amaraso adasanzwe kubera umubare wa platine wagabanutse.Gutwika cyane mumaso bita "uveitis" bishobora kubaho bitewe nigihe kirekire cyo gukingira indwara.Ingaruka zo mu mutwe zishobora no kugaragara.
Kwipimisha neza kanseri ya Ehrlichia bisaba kwiyumvisha morula muri monocytes kuri cytologiya, gutahura antibodiyumu ya E. canis serumu hamwe na test ya antibody ya immunofluorescence itaziguye (IFA), uburyo bwa polymerase bwerekana reaction (PCR), hamwe na / cyangwa gel blotting (Western immunoblotting).
Intandaro yo kwirinda kanseri ehrlichiose ni ukurwanya amatiku.Umuti uhitamo kuvura uburyo bwose bwa ehrlichiose ni doxycycline byibuze ukwezi.Hagomba kubaho iterambere rikomeye mu masaha 24-48 nyuma yo gutangira kuvurwa imbwa zifite uburwayi bukabije cyangwa bworoshye.Muri iki gihe, umubare wa platine utangira kwiyongera kandi ugomba kuba ibisanzwe mugihe cyiminsi 14 nyuma yo gutangira kwivuza.
Nyuma yo kwandura, birashoboka kongera kwandura;ubudahangarwa ntiburamba nyuma yo kwandura kwabanje.
Uburyo bwiza bwo kwirinda ehrlichiose ni ukurinda imbwa amatiku.Ibi bigomba kubamo kugenzura uruhu buri munsi amatiku no kuvura imbwa ukoresheje amatiku.Kubera ko amatiku atwara izindi ndwara zangiza, nk'indwara ya Lyme, anaplasmose na Rocky Mountain yagaragaye, ni ngombwa ko imbwa zitagira amatiku.