Inomero ya Cataloge | RC-CF31 |
Incamake | Kumenya antine ya Canine Dirofilaria immitis, antibodiyite za Anaplasma, antibodiyite za E. canis na LSH mu minota 10 |
Ihame | Intambwe imwe yubudahangarwa bw'umubiri |
Intego zo Kumenya | CHW Ag: Dirofilaria immitis antigens Anapalsma Ab: Antibodies za AnaplasmaE. canis Ab: E. antibodiyite LSH Ab: L. chagasi, L. infantum, na L. donovani antiboies |
Icyitegererezo | Canine Amaraso Yuzuye, Plasma cyangwa Serumu |
Igihe cyo gusoma | Iminota 10 |
Umubare | Agasanduku 1 (kit) = ibikoresho 10 (Gupakira kugiti cyawe) |
Ibirimo | Ikizamini cyibizamini, icupa rya Buffer, hamwe nigitonyanga |
Ububiko | Ubushyuhe bwo mucyumba (kuri 2 ~ 30 ℃) |
Igihe kirangiye | Amezi 24 nyuma yo gukora |
Icyitonderwa | Koresha muminota 10 nyuma yo gufunguraKoresha urugero rwicyitegererezo (0,01 ml yigitonyanga) Koresha nyuma yiminota 15 ~ 30 kuri RT niba bibitswe mubihe bikonje Reba ibisubizo by'ibizamini bitemewe nyuma yiminota 10 |
Indwara z'umutima zikuze zikura santimetero nyinshi z'uburebure kandi ziba mu mitsi iva mu bihaha aho ishobora kubona intungamubiri zihagije.Indwara z'umutima ziri mu mitsi zitera gucana no gukora hematoma.Umutima rero, ugomba kuvoma kenshi kuruta mbere nkuko inzoka zumutima ziyongera mumibare, bikabuza imiyoboro.
Iyo kwandura kwangiritse (inzoka zirenga 25 zibaho mu mbwa 18 kg), inzoka zumutima zinjira muri atrium iburyo, bikabuza gutembera kwamaraso.
Iyo umubare winzoka zumutima ugeze kurenga 50, barashobora gufata
atrium na ventricles.
Iyo yanduye indwara zumutima zirenga 100 mugice cyiburyo cyumutima, imbwa itakaza imikorere yumutima amaherezo igapfa.Ibi byica
phenomenon yitwa "Syndrom ya Caval."
Bitandukanye nizindi parasite, inzoka zumutima zitera udukoko duto bita microfilariya.Microfilariya mu mibu yimukira mu mbwa iyo umubu unywa amaraso n'imbwa.Indwara z'umutima zishobora kubaho mubakira imyaka 2 zipfa iyo zitimukiye mubandi bakiriye muri kiriya gihe.Parasite iba mu mbwa itwite irashobora kwanduza urusoro rwayo.
Gusuzuma hakiri kare inzoka z'umutima ni ngombwa cyane mu kuzikuraho.Indwara z'umutima zinyura mu ntambwe nyinshi nka L1, L2, L3 harimo icyiciro cyo kwanduza imibu kugirango kibe inzoka z'umutima zikuze.
Microfilariya mu mibu ikura muri L2 na L3 parasite zishobora kwanduza imbwa mu byumweru byinshi.Gukura biterwa nikirere.Ubushyuhe bwiza kuri parasite burenga 13.9 ℃.
Iyo umubu wanduye urumye imbwa, microfilariya ya L3 yinjira mu ruhu rwayo.Mu ruhu, microfilariya ikura muri L4 ibyumweru 1 ~ 2.Nyuma yo kuba mu ruhu amezi 3, L4 ikura muri L5, ijya mumaraso.
L5 nkuburyo bwinzoka zumutima zikuze zinjira mumutima no mumitsi yimitsi aho amezi 5 ~ 7 nyuma yumutima utera udukoko.
Amateka yindwara namakuru yubuvuzi bwimbwa irwaye, nuburyo butandukanye bwo gusuzuma bugomba gutekerezwa mugupima imbwa.Kurugero, X-ray, scan ya ultrasound, gusuzuma amaraso, gutahura microfilariya kandi, mubihe bibi, hakenewe autopsie.
Ikizamini cya serumu;
Kumenya antibodies cyangwa antigene mumaraso
Ikizamini cya antigen;
Ibi byibanda ku kumenya antigene yihariye yinzoka yumutima ukuze.Ikizamini gikorerwa mu bitaro kandi intsinzi yayo ni myinshi.Ibikoresho byo kwipimisha biboneka kumasoko byashizweho kugirango hamenyekane inzoka zumutima zamezi 7 ~ 8 kugirango inzoka zumutima zirengeje amezi 5 ziragoye kubimenya.
Indwara yinzoka yumutima irakira neza mubihe byinshi.Kurandura inzoka zose z'umutima, gukoresha imiti ninzira nziza.Kumenya hakiri kare inzoka z'umutima bizamura igipimo cyo kuvura.Ariko, mugihe cyanyuma cyo kwandura, ingorane zirashobora kubaho, bigatuma kuvura bigorana.
Bagiteri Anaplasma phagocytophilum (yahoze yitwa Ehrilichia phagocytophila) irashobora gutera kwandura amoko menshi y’inyamaswa harimo n’abantu.Indwara iri mu matungo yo mu rugo nayo yitwa tick-borne fever (TBF), ikaba imaze nibura imyaka 200.Indwara ya bagiteri yumuryango Anaplasmataceae ni garama-mbi, idafite moteri, coccoide yibinyabuzima bya ellipsoide, bitandukanye mubunini kuva kuri 0.2 kugeza kuri 2.0um.Nibitegekwa na aerobes, kubura inzira ya glycolitike, kandi byose ni parasite idasanzwe.Amoko yose yo mu bwoko bwa Anaplasma atuye muri vacuole itondekanye muri selile zidakuze cyangwa zikuze za hematopoietic ya selile y’inyamabere.Phagocytophilum yanduza neutrophile kandi ijambo granulocytotropic ryerekeza kuri neutrophile yanduye.Ni gake ibinyabuzima, byabonetse muri eosinofile.
Anaplasma phagocytophilum
Ibimenyetso bisanzwe byubuvuzi byaCanine anaplasmose irimo umuriro mwinshi, ubunebwe, depression na polyarthritis.Ibimenyetso bya neurologic (ataxia, gufatwa no kubabara ijosi) nabyo birashobora kugaragara.Indwara ya Anaplasma phagocytophilum ntishobora guhitana abantu keretse iyo igoye nizindi ndwara.Igihombo kiziguye, ubumuga bwo gutakaza no gutakaza umusaruro byagaragaye muntama.Gukuramo inda no kwangirika kwa spermatogenezi mu ntama n'inka byanditswe.Uburemere bwubwandu buterwa nimpamvu nyinshi, nkimpinduka za Anaplasma phagocytophilum zirimo, izindi ndwara ziterwa na virusi, imyaka, imiterere yumubiri ndetse nubuzima bwa nyirubwite, nibintu nkikirere nubuyobozi.Twabibutsa ko ivuriro ryigaragaza mu bantu ritangirira ku ndwara yoroheje yibicurane nk'ibicurane, kugeza n'indwara yangiza ubuzima.Nyamara, indwara nyinshi zabantu zishobora kuvamo bike cyangwa ntabigaragaza.
Anaplasma phagocytophilum yanduzwa na tike ya ixodide.Muri Reta zunzubumwe zamerika ibice nyamukuru ni Ixode scapularis na Ixode pacificus, mugihe Ixode ricinus yasanze aribwo buryo nyamukuru bwa exophilique i Burayi.Anaplasma phagocytophilum yanduzwa naya matiku ya vector, kandi nta kimenyetso cyerekana kwandura transovarial.Ubushakashatsi bwinshi kugeza ubu bwakoze ubushakashatsi ku kamaro k’inyamabere z’inyamabere za A. phagocytophilum hamwe n’ingirabuzimafatizo zayo byibanze ku nzoka ariko iki kinyabuzima gifite inyamaswa nini z’inyamabere, zanduza injangwe zororerwa mu rugo, imbwa, intama, inka, n'amafarasi.
Indirect immunofluorescence isuzuma nikizamini nyamukuru gikoreshwa mugutahura ubwandu.Icyiciro cya serumu ikaze kandi ihindagurika irashobora gusuzumwa kugirango harebwe impinduka enye muri titer ya antibody kuri Anaplasma phagocytophilum.Imitsi idasanzwe (morulea) igaragara muri granulocytes kuri Wright cyangwa Gimsa isize amaraso.Uburyo bwa polymerase reaction (PCR) bukoreshwa mugutahura ADN ya Anaplasma phagocytophilum.
Nta rukingo ruboneka kugirango wirinde kwandura Anaplasma phagocytophilum.Kwirinda bishingiye ku kwirinda kwirinda kwandura amatiku (Ixode scapularis, Ixode pacificus, na Ixode ricinus) kuva mu mpeshyi kugeza kugwa, gukoresha imiti igabanya ubukana bwa antacariside, no gukoresha poropagitike ya doxycycline cyangwa tetracycline igihe usuye Ixode scapularis, Ixode pacificus, na Ixode ricxin uturere twanduye.
Ehrlichia canis ni parasite ntoya ninkoni yanduzwa nimbwa yimbwa yumukara, Rhipicephalus sanguineus.E. canis nintandaro ya ehrlichiose ya kera mu mbwa.Imbwa zirashobora kwandura spp nyinshi za Ehrlichia.ariko ikunze gutera kanseri ehrlichiose ni E. canis.
E. canis ubu bizwi ko yakwirakwiriye muri Amerika, Uburayi, Amerika y'Epfo, Aziya na Mediterane.
Imbwa zanduye zitavuwe zirashobora guhinduka abatwara indwara imyaka myinshi hanyuma amaherezo igapfa kubera kuva amaraso menshi.
Indwara ya Ehrlichia canis mu mbwa igabanijwemo ibyiciro 3;
ICYICIRO CYA ACUTE: Mubisanzwe nicyiciro cyoroheje cyane.Imbwa izaba idafite urutonde, ibiryo, kandi irashobora kuba yaguye lymph node.Hashobora no kugira umuriro ariko gake ni gake iki cyiciro cyica imbwa.Benshi basiba ibinyabuzima bonyine ariko bamwe bazakomeza mugice gikurikira.
ICYICIRO CYA SUBCLINICAL: Muri iki cyiciro, imbwa igaragara nkibisanzwe.Ibinyabuzima byacengeye mu ruhago kandi byihishe hanze.
ICYICIRO CYA CHRONIC: Muri iki cyiciro imbwa irongera irarwara.Imbwa zigera kuri 60% zanduye E. canis zizagira amaraso adasanzwe kubera umubare wa platine wagabanutse.Gutwika cyane mumaso bita "uveitis" bishobora kubaho bitewe nigihe kirekire cyo gukingira indwara.Ingaruka zo mu mutwe zishobora no kugaragara.
Kwipimisha neza kanseri ya Ehrlichia bisaba kwiyumvisha morula muri monocytes kuri cytologiya, gutahura antibodiyumu ya E. canis serumu hamwe na test ya antibody ya immunofluorescence itaziguye (IFA), uburyo bwa polymerase bwerekana reaction (PCR), hamwe na / cyangwa gel blotting (Western immunoblotting).
Intandaro yo kwirinda kanseri ehrlichiose ni ukurwanya amatiku.Umuti uhitamo kuvura uburyo bwose bwa ehrlichiose ni doxycycline byibuze ukwezi.Hagomba kubaho iterambere rikomeye mu masaha 24-48 nyuma yo gutangira kuvurwa imbwa zifite uburwayi bukabije cyangwa bworoshye.Muri iki gihe, umubare wa platine utangira kwiyongera kandi ugomba kuba ibisanzwe mugihe cyiminsi 14 nyuma yo gutangira kwivuza.
Nyuma yo kwandura, birashoboka kongera kwandura;ubudahangarwa ntiburamba nyuma yo kwandura kwabanje.
Uburyo bwiza bwo kwirinda ehrlichiose ni ukurinda imbwa amatiku.Ibi bigomba kubamo kugenzura uruhu buri munsi amatiku no kuvura imbwa ukoresheje amatiku.Kubera ko amatiku atwara izindi ndwara zangiza, nk'indwara ya Lyme, anaplasmose na Rocky Mountain yagaragaye, ni ngombwa ko imbwa zitagira amatiku.
Leishmaniyasi nindwara ikomeye kandi ikomeye ya parasitike yabantu, kineine na fine.Umukozi wa leishmaniyasi ni parasite ya protozoan kandi ni iy'ikigo cya leishmania donovani.Iyi parasite ikwirakwizwa cyane mu bihugu bituje kandi bishyuha byo mu Burayi bw'Amajyepfo, Afurika, Aziya, Amerika y'Epfo na Amerika yo Hagati.Leishmania donovani infantum (L. infantum) ishinzwe indwara ya feline na kineine mu Burayi bw'Amajyepfo, Afurika, na Aziya.Canine Leishmaniasis n'indwara ikomeye itera imbere.Imbwa zose ntabwo zirwara indwara zamavuriro nyuma yo guterwa na parasite.Iterambere ryindwara zamavuriro riterwa nubwoko bwikingira ryinyamaswa zinyamaswa zifite
kurwanya parasite.
Muri Canine
Byombi bigaragara kandi byerekanwa bishobora kuboneka icyarimwe imbwa;bitandukanye nabantu, syndromes itandukanye ya caneane na visceral ntabwo igaragara.Ibimenyetso byamavuriro birahinduka kandi birashobora kwigana izindi ndwara.Indwara zidafite ibimenyetso nazo zirashobora kubaho.Ibimenyetso bisanzwe byimyanya ndangagitsina bishobora kuba birimo umuriro (bishobora kuba rimwe na rimwe), kubura amaraso, lymphadenopathie, splenomegaly, ubunebwe, kugabanuka kwihanganira imyitozo ngororamubiri, kugabanya ibiro, no kurya.Ibimenyetso bidakunze kugaragara harimo impiswi, kuruka, melena, glomerulonephritis, kunanirwa kw'umwijima, epistaxis, polyuria-polydipsia, kuniha, gucumbagira (kubera polyarthrite cyangwa myosite), asite, na kolite idakira.
Muri Feline
Ni gake injangwe zanduye.Mu njangwe nyinshi zanduye, ibikomere bigarukira gusa ku bisebe byanduye, bikunze kuboneka ku minwa, izuru, ijisho, cyangwa pinnae.Ibibyimba bya visceral nibimenyetso ntibisanzwe.
Inzira yubuzima irangizwa mubice bibiri.Intangangabo zintangangabo hamwe nintegamubiri zidafite ubuzima (isazi yumusenyi).Isazi yumucanga wigitsina gore igaburira intanga ngabo kandiyinjiza amastigote.Ibendera ryamamaye ritera imbere muri ako gakoko.Promastigote yatewe muri nyababyeyi mugihe cyo kugaburira umusenyi.Promastigote ikura muri amastigote kandi igwira cyane cyane muri macrophage.Kugwiza muri macrophage yuruhu, mucosa na viscera, bitera kanseri, mucosal na visceral leishmaniasis.
Mu mbwa, indwara ya leishmaniyasi isuzumwa no kureba neza parasite, ukoresheje Giemsa cyangwa ibintu byihuta byihuta, mu gusiga amavuta ya lymph node, spleen, cyangwa amagufwa yo mu magufa, biopies tissue, cyangwa ibikomere by'uruhu biturutse ku bisebe.Ibinyabuzima birashobora kandi kuboneka muri ocular lesions, cyane cyane muri granuloma.Amastigote irazengurutse ova parasite, hamwe na nucleus ya basofilique izengurutse hamwe na kinetoplast ntoya.Baboneka muri macrophage cyangwa bakuwe mu ngirabuzimafatizo.Immunohistochemie na polymerase urunigi rwa reaction (PCR) nabyo birakoreshwa.
Imiti ikoreshwa cyane ni: Meglumine Antimoniate ifitanye isano na Allopurinol, Aminosidine, na vuba aha, Amphotericin B. Iyi miti yose isaba uburyo bwinshi bwo kunywa, kandi ibyo bizaterwa nuburwayi ndetse nubufatanye bwa nyirubwite.Hasabwe ko ubuvuzi bwibanze bugomba kubikwa hamwe na allopurinol, kubera ko bidashoboka kwemeza ko imbwa zitazasubira mu gihe ubuvuzi bwahagaritswe.Gukoresha amakariso arimo udukoko twica udukoko, shampo cyangwa spray bigira akamaro ko kurinda imbwa kurumwa numusenyi bigomba guhora bikoreshwa kubarwayi bose bavurwa.Kugenzura vector ni kimwe mu bintu by'ingenzi bigamije kurwanya indwara.
Umusenyi wibasiwe nudukoko twica malariya.